| Identification | More | [Name]
2,6-Difluorobenzamide | [CAS]
18063-03-1 | [Synonyms]
2,6-DIFLUOROBENZAMIDE
2,6-difluoro-benzamid
2，6-difluorobenzaminde
2,6-difluorobenzoic acid amide
2,6-Difluorobenzamide97%
2,6-Difluorbenzamid
2,6-Difluorobenzoylamide
2,6-DIFLUOROBENZAMIDE, 98+% | [EINECS(EC#)]
241-972-8 | [Molecular Formula]
C7H5F2NO | [MDL Number]
MFCD00007972 | [Molecular Weight]
157.12 | [MOL File]
18063-03-1.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20:Harmful by inhalation. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
1
| [RTECS ]
CV4355050
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29242990 | [Toxicity]
rat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293, |
| Hazard Information | Back Directory | [Description]
2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method. | [Chemical Properties]
white powder | [Uses]
2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids. | [Preparation]
2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile. | [General Description]
2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method. | [Toxics Screening Level]
The Initial Threshold Screening Level (ITSL) for 2,6-Difluorobenzamide is 11 μg/m3 based on an annual averaging time. | [References]
[1] Straniero V, et al. 2,6-Difluorobenzamide inhibitors of the bacterial cell division protein FtsZ: design, synthesis and
Structure Activity Relationship study. ChemMedChem, 2017; 12: 1303-1318. |
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