| Identification | Back Directory | [Name]
GANGLIOSIDE GM2 SODIUM SALT | [CAS]
19600-01-2 | [Synonyms]
GM2 NA
Ganglioside G5
GANGLIOSIDE GM2
g(m2)ganglioside
Tay-Sachs ganglioside
MONOSIALOGANGLIOSIDE GM2
CER GLC GAL(NEUAC) GALNAC
GANGLIOSIDE GM2, MONOSIALO
GANGLIOSIDE GM2 SODIUM SALT
MONOSIALOGANGLIOSIDE GM2, HUMAN
MONOSIALOGANGLIOSIDE GM2, BOVINE
GANGLIOSIDE GM2 (NEUAC)SODIUM SALT
Sialosylganglio-N-triaosylceramide
MONOSIALOGANGLIOSIDE GM2 NA (BOVINE)
MONOSIALOGANGLIOSIDE GM2 SODIUM SALT
GANGLIOSIDEGM2SODIUMSALT,BOVINEBRAIN
Monosialoganglioside GM2 bovine brain
Ganglioside GM2 Mixture (sodium salt)
monosialoganglioside G(M2) from bovine brain
MONOSIALOGANGLIOSIDE-GM2 CELL CULTURE*TE STED
GANGLIOSIDEGM2SODIUMSALT,BOVINEBRAIN,CELLCULTUREGRADE
GANGLIOSIDE GM2 (NEUAC)SODIUM SALT, FROM BOVINE BRAIN
Ganglioside GM2 Mixture (bovine brain) (ammonium salt) | [Molecular Formula]
C68H123N3O26 | [MDL Number]
MFCD00131137 | [MOL File]
19600-01-2.mol | [Molecular Weight]
1398.71 |
| Hazard Information | Back Directory | [Uses]
Monosialoganglioside GM2 from bovine brain has been used:
- to study the effects of GM2 supplementation and depletion of all cellular ganglioside subspecies on neurite outgrowth and neuronal survival using canine dorsal root ganglia (DRG) neurons
- as a reference standard for high-performance thin-layer chromatography (HPTLC) and as antigens for enzyme-linked immunosorbent assay (ELISA) to analyze the ganglioside signatures of human prostate cancer (CaP) cells
- as a component of the reaction buffer to perform in vitro activity assay of GM1 synthase
| [General Description]
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980. | [Biochem/physiol Actions]
Minor component of cell membranes that has been shown to accumulate in Tay-Sachs disease. |
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