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2113650-05-6

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2113650-05-6 Structure

2113650-05-6 Structure
IdentificationBack Directory
[Name]

BMS-1166 HCl
[CAS]

2113650-05-6
[Synonyms]

BMS-1166 HCl
BMS-1166 hydrochloride
BMS1166 HCL;BMS 1166 HCL
BMS-1166 hydrochloride (BMS1166 Hcl
[Molecular Formula]

C36H34Cl2N2O7
[MDL Number]

MFCD32201026
[MOL File]

2113650-05-6.mol
[Molecular Weight]

677.58
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor. BMS-1166 binds to human PD-L1 and blocks its interaction with PD-1. BMS-1166 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. Moreover, BMS-1166 was effective in attenuating the inhibitory effect of the cell surface-associated PD-L1.
[target]

BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor.
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