2113650-05-6
中文名称
BMS-1166 HCl
英文名称
BMS-1166 HCl
CAS
2113650-05-6
分子式
C36H34Cl2N2O7
分子量
677.58
MOL 文件
2113650-05-6.mol
更新日期
2024/08/11 14:29:42
2113650-05-6 结构式
基本信息
中文别名
化合物 T14670 英文别名
BMS-1166 HClBMS-1166 hydrochloride
BMS1166 HCL
BMS 1166 HCL
BMS-1166 hydrochloride (BMS1166 Hcl
应用领域
用途一
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor. BMS-1166 binds to human PD-L1 and blocks its interaction with PD-1. BMS-1166 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. Moreover, BMS-1166 was effective in attenuating the inhibitory effect of the cell surface-associated PD-L1.