ChemicalBook--->CAS DataBase List--->2158322-29-1

2158322-29-1

2158322-29-1 Structure

2158322-29-1 Structure
IdentificationBack Directory
[Name]

PROTAC ER Degrader-3
[CAS]

2158322-29-1
[Synonyms]

PROTAC ER Degrader-3
[Molecular Formula]

C??H??N?O??
[MDL Number]

MFCD32067948
[MOL File]

2158322-29-1.mol
[Molecular Weight]

1220.43
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Description]

PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

[References]

[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.

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