ChemicalBook--->CAS DataBase List--->2378258-52-5

2378258-52-5

2378258-52-5 Structure

2378258-52-5 Structure
IdentificationBack Directory
[Name]

PROTAC K-Ras Degrader-1
[CAS]

2378258-52-5
[Synonyms]

K-Ras Degrader-1
PROTAC K-Ras Degrader-1
[Molecular Formula]

C53H62N10O10
[MDL Number]

MFCD32263411
[MOL File]

2378258-52-5.mol
[Molecular Weight]

999.14
Chemical PropertiesBack Directory
[density ]

1.40±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 33.33 mg/mL (33.36 mM)
[form ]

Solid
[pka]

10.74±0.40(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].

[storage]

Store at -20°C
[References]

[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.

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