| Identification | Back Directory | [Name]
YKL-06-062 | [CAS]
2172617-16-0 | [Synonyms]
YKL-06-062
Pyrimido[4,5-d]pyrimidin-2(1H)-one, 1-cyclohexyl-3-(2,6-dimethylphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]- | [Molecular Formula]
C31H39N7O | [MDL Number]
MFCD32263406 | [MOL File]
2172617-16-0.mol | [Molecular Weight]
525.69 |
| Chemical Properties | Back Directory | [Boiling point ]
706.2±70.0 °C(Predicted) | [density ]
1.229±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
7.90±0.42(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
YKL-06-062 is a second-generation SIK inhibitor. YKL 06-062 induces significant pigmentation after 8 days of treatment (1×/day). YKL 06-062 did not require mechanical application (rubbing) to induce significant human epidermal darkening. YKL-06-062 induces not only synthesis of melanin but also melanosomal maturation, export, and localization features, even after import into keratinocytes. | [storage]
Store at -20°C |
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