2172617-16-0
中文名称
YKL-06-062
英文名称
YKL-06-062
CAS
2172617-16-0
分子式
C31H39N7O
分子量
525.69
MOL 文件
2172617-16-0.mol
更新日期
2023/03/20 15:41:23
2172617-16-0 结构式
基本信息
中文别名
化合物 T17272 英文别名
YKL-06-062Pyrimido[4,5-d]pyrimidin-2(1H)-one, 1-cyclohexyl-3-(2,6-dimethylphenyl)-3,4-dihydro-7-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-
物理化学性质
沸点706.2±70.0 °C(Predicted)
密度1.229±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)7.90±0.42(Predicted)
形态Solid
颜色Light yellow to yellow
应用领域
用途一
YKL-06-062 is a second-generation SIK inhibitor. YKL 06-062 induces significant pigmentation after 8 days of treatment (1×/day). YKL 06-062 did not require mechanical application (rubbing) to induce significant human epidermal darkening. YKL-06-062 induces not only synthesis of melanin but also melanosomal maturation, export, and localization features, even after import into keratinocytes.