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2182601-20-1

2182601-20-1 Structure

2182601-20-1 Structure
IdentificationBack Directory
[Name]

Biotin-PEG8-alcohol
[CAS]

2182601-20-1
[Synonyms]

Biotin-PEG8-alcohol
[Molecular Formula]

C26H49N3O10S
[MDL Number]

MFCD31380394
[MOL File]

2182601-20-1.mol
[Molecular Weight]

595.75
Chemical PropertiesBack Directory
[Boiling point ]

794.3±60.0 °C(Predicted)
[density ]

1.167±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Water, DMSO, DMF, DCM
[form ]

Oil
[pka]

13.90±0.40(Predicted)
[color ]

Colorless to off-white
Hazard InformationBack Directory
[Description]

Biotin-PEG8-alcohol is an aqueous soluble reagent with a terminal primary hydroxyl (?OH) that reacts with a variety of functional groups.
[Uses]

Biotin-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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