Identification | More | [Name]
N-Isopropylacrylamide | [CAS]
2210-25-5 | [Synonyms]
AKOS 91289 Isopropyl acrylamide ISOPROPYLACRYLAMIDE(N-) NIPAM N-ISOPROPYLACRYLAMIDE 2-Propenamide, N-(1-methylethyl)- Isopropylamid kyseliny akrylove isopropylamidkyselinyakrylove n-(1-methylethyl)-2-propenamid N-(1-methylethyl)-2-Propenamide n-isopropyl-acrylamid Acrylamide, N-isopropyl. N-Isopropylacrylamide, stabilized, pure, 99% N-Isopropylacrylamide ,99% [pure,stabilized] N-ISOPROPYLACRYLAMIDE, 99%, STABILIZED, PURE | [EINECS(EC#)]
218-638-5 | [Molecular Formula]
C6H11NO | [MDL Number]
MFCD00041913 | [Molecular Weight]
113.16 | [MOL File]
2210-25-5.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystalline powder or | [Melting point ]
60-63 °C(lit.)
| [Boiling point ]
89-92 °C2 mm Hg(lit.)
| [density ]
1.0223 (rough estimate) | [refractive index ]
1.4210 (estimate) | [storage temp. ]
0-6°C | [form ]
Crystalline Powder or Crystals | [pka]
14.83±0.46(Predicted) | [color ]
White to light yellow | [PH]
pH(50g/l, 25℃) : 7.8~10.0 | [Water Solubility ]
Slightly soluble in water. | [Detection Methods]
HPLC,GC,NMR | [InChIKey]
QNILTEGFHQSKFF-UHFFFAOYSA-N | [LogP]
0.278 (est) | [Uses]
Binders in textiles, paper, adhesives, detergents, cosmetics. | [CAS DataBase Reference]
2210-25-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Acrylamide, n-isopropyl-(2210-25-5) | [Storage Precautions]
Heat sensitive | [EPA Substance Registry System]
2210-25-5(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. R36:Irritating to the eyes. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
AS3675000
| [TSCA ]
Yes | [HS Code ]
29241990 | [Hazardous Substances Data]
2210-25-5(Hazardous Substances Data) |
Hazard Information | Back Directory | [Description]
N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST). | [Chemical Properties]
white to light yellow crystalline powder or | [Application]
N-Isopropylacrylamide (NIPAM) can be used to prepare poly(NIPAM) based thermosetting polymers, which can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels. | [General Description]
N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties. These properties include temperature based volumetric and phase changes, which change when the temperature of the solution reaches a lower critical solution temperature (LCST). | [Flammability and Explosibility]
Notclassified | [Purification Methods]
Fractionate the amide under reduced pressure, and recrystallise the solid distillate from hexane (m 59o), *C6H6 (m 62o) or *C6H6/hexane (m 62-63o). Store it with 0.05% of 4-tert-butylcatechol. It is used for making water soluble swellable hydrogels. [Beilstein 4 IV 517.] |
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