ChemicalBook--->CAS DataBase List--->2363-58-8

2363-58-8

2363-58-8 Structure

2363-58-8 Structure
IdentificationBack Directory
[Synonyms]

10275S
Thiodrol
NSC 194684
Epitiostano
EPitostsanol
Epitiostanol
Epithiostanol
Epitiostanol RS
Epithioandrostanol
Epitiostanol USP/EP/BP
2α,3α-Epithio-5α-androstan-17β-ol
2,3-Epithio-1H-cyclopenta[a]phenanthrene
(2α,3α,5α,17β)-2,3-Epithioandrostan-17-ol
Androstan-17-ol,2,3-epithio-, (2a,3a,5a,17b)-
5α-Androstan-17β-ol, 2α,3α-epithio- (7CI, 8CI)
Androstan-17-ol, 2,3-epithio-, (2α,3α,5α,17β)-
2alpha,3alpha-Epithio-5alpha-androstan-17beta-ol
Epitiostanol (Contains up to 15% 3α,4α-Epithioandrostan Isomer)
2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstan-17-ol deriv.
[Molecular Weight]

306.51
Chemical PropertiesBack Directory
[density ]

1.0122 (rough estimate)
[refractive index ]

1.5700 (estimate)
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Potassium hydroxide-->Androst-2-en-17-one-->ANDROSTA-1,4,6-TRIENE-3,17-DIONE-->Epiandrosterone
[Preparation Products]

BETA-ESTRADIOL 17-ACETATE-->Boldenone 17-acetate
Hazard InformationBack Directory
[Uses]

An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.
[Definition]

ChEBI: Epitiostanol is an organic molecular entity.
[Manufacturing Process]

A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17- acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while stirring. To the reaction mixture, there is added water, and the separated substance is collected by filtration and crystallized from hexane to give 2β,3β- epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at 132.5°C to 134°C.
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