| Chemical Properties | Back Directory | [Boiling point ]
983.9±65.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [form ]
Oil | [pka]
12.28±0.20(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14) and no other proteins were significantly degraded. |
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