| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20mg/mL; DMF:PBS (pH 7.2) (1:2): 0.3mg/mL; DMSO: 5mg/mL; Ethanol: 12mg/mL | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
CAY10744 is a topoisomerase II-α poison. It inhibits topoisomerase II-α by 78.9% when used at a concentration of 20 μM. CAY10744 is selective for topoisomerase II-α over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 μM. It inhibits proliferation of HCT15 colon, T47D breast, DU145 prostate, and HeLa cervical cancer cells. |
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