2375613-31-1
2375613-31-1 结构式
物理化学性质
储存条件-20°C储存
溶解度DMF: 20mg/mL; DMF:PBS (pH 7.2) (1:2): 0.3mg/mL; DMSO: 5mg/mL; Ethanol: 12mg/mL
形态结晶固体
应用领域
用途一
CAY10744 is a topoisomerase II-α poison. It inhibits topoisomerase II-α by 78.9% when used at a concentration of 20 μM. CAY10744 is selective for topoisomerase II-α over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 μM. It inhibits proliferation of HCT15 colon, T47D breast, DU145 prostate, and HeLa cervical cancer cells.