ChemicalBook--->CAS DataBase List--->25249-16-5

25249-16-5

25249-16-5 Structure

25249-16-5 Structure
IdentificationBack Directory
[Name]

POLY(2-HYDROXYETHYL METHACRYLATE)
[CAS]

25249-16-5
[Synonyms]

POLY-HEMA
POLY(2-HEMA)
12%solutioninethanol
CELLFORM(TM) POLYMER
Poly(2-HEMA), Poly-HEMA
polyhydroxyethylmethacrylate
POLY(2-HYDROXYETHYL METHACRYLATE)
2-HYDROXYETHYL METHACRYLATE POLYMER
Poly(2-hydroxyethylmethacrylate)powder
2-hydroxyethyl methacrylate homopolymer
POLY(2-HYDROXYETHYL METHACRYLATE), MV CA
poly(2-hydroxyethyl methacrylate) macromolecule
POLY(2-HYDROXYETHYL METHACRYLATE) CELL*C ULTURE TEST
Poly(2-hydroxyethyl Methacrylate) average Mv ~20,000
Poly(2-hydroxyethyl methacrylate) Standard (Mw 2,000)
Poly(2-hydroxyethyl methacrylate) Standard (Mw 5,000)
POLY(2-HYDROXYETHYL METHACRYLATE) ISO 9001:2015 REACH
Poly(2-hydroxyethyl methacrylate) Standard (Mw 10,000)
Poly(2-hydroxyethyl methacrylate) Standard (Mw 20,000)
Poly(2-hydroxyethyl methacrylate) Standard (Mw 90,000)
Poly(2-hydroxyethyl methacrylate) Standard (Mw 200,000)
Poly(2-hydroxyethyl Methacrylate) average Mv ~1,000,000
Poly(2-hydroxyethyl methacrylate) Standard (Mw 400,000)
Poly(2-hydroxyethyl methacrylate),Poly(2-HEMA), Poly-HEMA
POLY(2-HYDROXYETHYL METHACRYLATE), AVERA GE MV CA. 300,000
Poly(2-hydroxyethyl Methacrylate) average Mv ~300,000, crystalline
[Molecular Formula]

C6H10O3
[MDL Number]

MFCD00084374
[MOL File]

25249-16-5.mol
[Molecular Weight]

130.14
Chemical PropertiesBack Directory
[density ]

1.15 g/mL at 25 °C(lit.)
[Tg]

55
[refractive index ]

1.5119
[storage temp. ]

4°C, away from moisture
[solubility ]

ethanol: 120 mg/mL
[form ]

powder
[color ]

White to off-white
[EPA Substance Registry System]

2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, homopolymer (25249-16-5)
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

pHEMA scaffolds are used in tissue engineering. It can be used in hydrogels for biomedical applications, as sorbents for metal ions.pHEMA has been used in applications such as soft contact lenses, in drug delivery systems, and in kidney dialysis membranes.Nanoparticles of pHEMA may be employed as a carrier for controlled delivery of anticancer and antitumor drugs.
[Uses]

Poly(2-hydroxyethyl methacrylate) has been used:
  • as a nonadhesive substrate in the preparation of single cell suspensions
  • to implant into mice cornea for corneal micropocket assay
  • to coat the well plates for sphere assay using adipose-derived mesenchymal stem cells

[Definition]

ChEBI: An acrylate macromolecule, composed of repeating 2-hydroxyethyl 2-methylpropanoate units.
[General Description]

Solid Poly(2-hydroxyethyl methacrylate) (pHEMA) is brittle, while pHEMA hydrogel is a soft material. Glass transition temperature for pHEMA hydrogels is reduced by increasing a content of water in the matrix. Macromolecular properties in pHEMA are characterized by non-covalent interactions of hydrogen-bonds among the polymer chains as well as the hydrated water molecules. The presence of polar groups of hydroxyl and carboxyl on each repeat unit makes this polymer compatible with water. The hydrophobic a-methyl groups of the backbone convey hydrolytic stability to the polymer and enhance mechanical strength of the polymer matrix.
[Biochem/physiol Actions]

Poly(2-hydroxyethyl methacrylate) is an acrylic compound and has dental usage. It is mainly used to inhibit cell adhesion to growth surfaces in culture vessels.
[Solubility in organics]

DMF, methanol, methyl cellosolve
Spectrum DetailBack Directory
[Spectrum Detail]

POLY(2-HYDROXYETHYL METHACRYLATE)(25249-16-5)Raman
POLY(2-HYDROXYETHYL METHACRYLATE)(25249-16-5)IR
POLY(2-HYDROXYETHYL METHACRYLATE)(25249-16-5)FT-IR
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