| Identification | More | [Name]
3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride | [CAS]
25629-50-9 | [Synonyms]
3-(2-CHLOROPHENYL)-5-METHYL-4-CHLOROCARBONYL ISOXAZOLE
3-(2-CHLOROPHENYL)-5-METHYL-4-ISOXAZOLE-CARBONYL CHLORIDE
3-(2-CHLOROPHENYL)-5-METHYL-4-ISOXAZOLECARBOXYLIC ACID CHLORIDE
3-(2-CHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBONYL CHLORIDE
LABOTEST-BB LT00848349
3-(2-chlorophenyl)-5-methyl-4-isoxazolecarbonylchlorid
3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride
3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride
3-(2-Chlorophenyl)-5-methyl-3-phenyl-4-chlorocarbonylisoxazole
3-(O-CHLOROPHENYL)-5-METHYL-4-CHLOROCARBONYLISOXAZOLE
3-(2-chlorophenyl)-5-methyl-4-isoxazolecarbonyl chlorid 3-(2-Chlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride 3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride
3-(2-CHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBONYL CHLORIDE, 98 | [EINECS(EC#)]
247-137-4 | [Molecular Formula]
C11H7Cl2NO2 | [MDL Number]
MFCD00020811 | [Molecular Weight]
256.08 | [MOL File]
25629-50-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Cream solid | [Melting point ]
41-42°C | [Boiling point ]
381.7±42.0 °C(Predicted) | [density ]
1.381±0.06 g/cm3(Predicted) | [vapor pressure ]
0.001Pa at 25℃ | [form ]
crystalline solid | [pka]
-5.80±0.50(Predicted) | [color ]
White to off-white | [Water Solubility ]
128.2mg/L at 25℃ | [Sensitive ]
Moisture Sensitive | [BRN ]
791931 | [InChI]
InChI=1S/C11H7Cl2NO2/c1-6-9(11(13)15)10(14-16-6)7-4-2-3-5-8(7)12/h2-5H,1H3 | [InChIKey]
BPDBLWKFVXHGFT-UHFFFAOYSA-N | [SMILES]
C(Cl)(C1=C(C)ON=C1C1=CC=CC=C1Cl)=O | [LogP]
2.61 at 25℃ | [CAS DataBase Reference]
25629-50-9(CAS DataBase Reference) | [EPA Substance Registry System]
25629-50-9(EPA Substance) |
| Safety Data | Back Directory | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
3261 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
2934999090 |
| Hazard Information | Back Directory | [Chemical Properties]
3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride is Cream solid
| [Uses]
3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride is used for preparing isoxazolyl penicillin derivatives.
| [Flammability and Explosibility]
Notclassified | [Synthesis]
To the solution was dropwise added under cooling at -12° to -14°C a solution of 3-(2-chlorophenyl)-5-methylisoxazol-4-carbonyl chloride, which was prepared from 3-(2-chlorophenyl)-5-methylisoxazol-4-carboxylic acid (1.78 g.) and thionyl chloride (10 ml.), in methylene chloride and then stirred for 5 hours. After the reaction, to the solution was added ice-water, and the resulant mixture was washed with water, dilute phosphoric acid, an aqueous solution of sodium bicarbonate and water in turn, and dried over magnesium sulfate. |
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