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324054-99-1

324054-99-1 Structure

324054-99-1 Structure
IdentificationBack Directory
[Name]

N-[2-(aminocarbonyl)phenyl][1,1'-biphenyl]-4-carboxamide
[CAS]

324054-99-1
[Synonyms]

N-(2-carbamoylphenyl)biphenyl-4-carboxamide
N-[2-(aminocarbonyl)phenyl][1,1'-biphenyl]-4-carboxamide
[1,1'-Biphenyl]-4-carboxamide, N-[2-(aminocarbonyl)phenyl]-
[Molecular Formula]

C20H16N2O2
[MDL Number]

MFCD00977705
[MOL File]

324054-99-1.mol
[Molecular Weight]

316.35
Hazard InformationBack Directory
[Description]

APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-L1 knock-in B16F10-bearing mouse model without the induction of observable liver toxicity.
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