Identification | Back Directory | [Name]
N-[2-(aminocarbonyl)phenyl][1,1'-biphenyl]-4-carboxamide | [CAS]
324054-99-1 | [Synonyms]
N-(2-carbamoylphenyl)biphenyl-4-carboxamide N-[2-(aminocarbonyl)phenyl][1,1'-biphenyl]-4-carboxamide [1,1'-Biphenyl]-4-carboxamide, N-[2-(aminocarbonyl)phenyl]- | [Molecular Formula]
C20H16N2O2 | [MDL Number]
MFCD00977705 | [MOL File]
324054-99-1.mol | [Molecular Weight]
316.35 |
Hazard Information | Back Directory | [Description]
APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-L1 knock-in B16F10-bearing mouse model without the induction of observable liver toxicity. |
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Specs
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