| Identification | More | [Name]
1-BROMO-2,4-DIFLUORO-5-NITROBENZENE | [CAS]
345-24-4 | [Synonyms]
AURORA KA-7912
BUTTPARK 89\07-60
4-DIFLUORO-5-NITROBENZENE
5-BROMO-2,4-DIFLUORONITROBENZENE
2,4-Difluoro-5-nitrobroMobenzene
2,4-Difluoro-5-BroMonitrobenzene
1-BROMO-2,4-DIFLUORO-5-NITROBENZENE
5-Bromo-2,4-difluoronitrobenzene 98%
Benzene, 1-broMo-2,4-difluoro-5-nitro- | [Molecular Formula]
C6H2BrF2NO2 | [MDL Number]
MFCD00129166 | [Molecular Weight]
237.99 | [MOL File]
345-24-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
19°C(lit.) | [Boiling point ]
85°C 0,4mm | [density ]
1.890±0.06 g/cm3(Predicted) | [refractive index ]
1.5580 to 1.5620 | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to lump to clear liquid | [color ]
White or Colorless to Light yellow | [CAS DataBase Reference]
345-24-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2904990090 |
| Hazard Information | Back Directory | [Uses]
1-Bromo-2,4-difluoro-5-nitrobenzene is a nitrobenzene derivative containing fluorine and bromine atom substituents. It can be used as a pharmaceutical intermediate for the preparation of novel N2-phenylpyrimidine-2,4-diamine compounds showing effective inhibition of EGFR mutations, and thus can be effectively used in the treatment of EGFR-mutated cancers. |
|
|