| Identification | More | [Name]
3-METHYL-L-HISTIDINE N-HYDRATE | [CAS]
368-16-1 | [Synonyms]
3-METHYL-L-HISTIDINE N-HYDRATE
3-methylhistidine
π-methyl-l-histidine
(2S)-2-amino-3-(3-methylimidazol-4-yl)propanoic acid
METHYL-L-HISTIDINE, 1-(RG)
METHYL-L-HISTIDINE, 3-(RG)
1-METHYL-L-HISTIDINE CRYSTALLINE
H-His(p-Me)-OH
π:-Methyl-L-histidine, 1-Methyl-L-histidine (archaic), 3-(1-Methylimidazol-5-yl)-L-alanine
(αS)-α-Amino-1-methyl-1H-imidazole-5-propionic acid
2,3-Dihydro-1,2-didehydro-Nπ-methyl-L-histidine | [EINECS(EC#)]
206-704-6 | [Molecular Formula]
C7H13N3O3 | [MDL Number]
MFCD08273564 | [Molecular Weight]
187.2 | [MOL File]
368-16-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
248～252℃ | [alpha ]
+12.0～+18.0°(20℃/D)(c=2,dil.HCl) | [Boiling point ]
298.47°C (rough estimate) | [density ]
1.37 | [refractive index ]
1.5950 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
2.04±0.10(Predicted) | [color ]
White to off-white | [Stability:]
Hygroscopic | [CAS DataBase Reference]
368-16-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
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| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
3-Methyl-L-histidine is a potential compound to be used as a treatment with pharmacological PPARα agonists to stimulate the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeleta l muscle of rodents.
| [Definition]
ChEBI: A L-histidine derivative that is L-histidine substituted by a methyl group at position 3 on the imidazole ring. | [Biochem/physiol Actions]
3-Methyl-L-histidine is a non-proteinogenic amino acid and an index of muscle breakdown. |
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