| Identification | More | [Name]
2-(Trifluoromethyl)pyridine | [CAS]
368-48-9 | [Synonyms]
2-(TRIFLUOROMETHYL)PYRIDINE
ALPHA,ALPHA,ALPHA-TRIFLUORO-2-PICOLINE
Pyridine, 2-(trifluoromethyl)-
à,à,à-trifluoro-2-picoline
α,α,α-trifluoro-2-picoline
2-trifluoromethylpyridine UNDRE RD
2-(CF3)-Pyridine | [EINECS(EC#)]
626-032-0 | [Molecular Formula]
C6H4F3N | [MDL Number]
MFCD02183562 | [Molecular Weight]
147.1 | [MOL File]
368-48-9.mol |
| Chemical Properties | Back Directory | [Boiling point ]
139-141 °C | [density ]
1.275 g/mL at 25 °C
| [refractive index ]
n20/D 1.419
| [Fp ]
109 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Soluble in most organic solvents. | [pka]
0.60±0.12(Predicted) | [Detection Methods]
GC | [BRN ]
3112 | [InChIKey]
ATRQECRSCHYSNP-UHFFFAOYSA-N | [CAS DataBase Reference]
368-48-9(CAS DataBase Reference) | [NIST Chemistry Reference]
2-(CF3)-pyridine(368-48-9) | [Storage Precautions]
Heat sensitive;Store under nitrogen |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,F | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [Hazard Note ]
Flammable/Irritant | [HazardClass ]
3 | [PackingGroup ]
III |
| Hazard Information | Back Directory | [Uses]
Lithiation with n-BuLi/LiOCH2CH2NMe2?takes place at the 6-position, affording access to 6-substituted derivatives. With LiTMP?. It is a building block in heterocycle synthesis. | [Synthesis Reference(s)]
Synthesis, p. 932, 1980 DOI: 10.1055/s-1980-29276 |
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