ChemicalBook--->CAS DataBase List--->37318-49-3

37318-49-3

37318-49-3 Structure

37318-49-3 Structure
IdentificationBack Directory
[Name]

EC 5.3.4.1
[CAS]

37318-49-3
[Synonyms]

PDI
DSBA
PDA2
PADI1
HPAD10
EC 5.3.4.1
LA16c-314G4.2
PAD1, GST tagged human
PROTEIN DISULFIDE ISOMERASE
Native Human Topoisomerase II α
Recombinant Disulfide Oxidoreductase
Anti-PDIA2 antibody produced in goat
protein disulfide isomerase from E. coli
THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA
Protein disulfide Isomerase bovine liver
Native Bovine Protein Disulfide Isomerase
CONNECTASH(TM) PROTEIN DISULFIDE-ISOMERASE
5-aminooxysulfonyl-2,4-dichlorobenzoic acid
PROTEIN DISULFIDE ISOMERASE, FROM BOVINE LIVER
protein disulfide isomerase family A, member 2
PROTEIN DISULFIDE ISOMERASE FROM E. COLI , 500 UG*
Protein Disulfide Isomerase from Human, Recombinant
Protein Disulfide Isomerase from bovine liver >95% (SDS-PAGE), >=100 units/mg protein, lyophilized powder
[Molecular Formula]

C7H5Cl2NO5S
[MDL Number]

MFCD00163364
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

lyophilized powder
Safety DataBack Directory
[WGK Germany ]

3
[F ]

3-10-21
Hazard InformationBack Directory
[Uses]

Protein Disulfide Isomerase from bovine liver has been used:
  • to study the functional role of PDI in parasite infection and the interaction between macrophage PDI and?L. chagasi
  • in the in vitro translation reaction for the generation of disulfide bonds
  • in insulin-disulfide reduction assay and peptide binding assay
  • as a positive control in thiol-disulfide oxidoreductase activity assay

[General Description]

Protein disulfide isomerase (PDI) from bovine liver is a homodimer with a molecular weight of 107 kDa with the monomer corresponding to 57 kDa. The isoelectric point (pI) is approximately 4.2. The enzyme is a glycoprotein with 12% total carbohydrate content comprising of mannose, galactose, N-acetyl neuraminic acid (NANA) and 2-acetamido-2-deoxyglucose. PDI is an ubiquitous redox chaperone enzyme. It belongs to the, thioredoxin superfamily and is high conserved.
[Biochem/physiol Actions]

Protein Disulfide Isomerase (PDI) is mainly located in the endoplasmic reticulum (ER), where it assists in protein-folding and thiol-disulfide exchanges. It aids protein refolding in vitro allowing recombinant proteins to achieve their native state.
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