Identification | Back Directory | [Name]
EC 5.3.4.1 | [CAS]
37318-49-3 | [Synonyms]
PDI DSBA PDA2 PADI1 HPAD10 EC 5.3.4.1 LA16c-314G4.2 PAD1, GST tagged human PROTEIN DISULFIDE ISOMERASE Native Human Topoisomerase II α Recombinant Disulfide Oxidoreductase Anti-PDIA2 antibody produced in goat protein disulfide isomerase from E. coli THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA Protein disulfide Isomerase bovine liver Native Bovine Protein Disulfide Isomerase CONNECTASH(TM) PROTEIN DISULFIDE-ISOMERASE 5-aminooxysulfonyl-2,4-dichlorobenzoic acid PROTEIN DISULFIDE ISOMERASE, FROM BOVINE LIVER protein disulfide isomerase family A, member 2 PROTEIN DISULFIDE ISOMERASE FROM E. COLI , 500 UG* Protein Disulfide Isomerase from Human, Recombinant Protein Disulfide Isomerase from bovine liver >95% (SDS-PAGE), >=100 units/mg protein, lyophilized powder | [Molecular Formula]
C7H5Cl2NO5S | [MDL Number]
MFCD00163364 |
Hazard Information | Back Directory | [Uses]
Protein Disulfide Isomerase from bovine liver has been used:
- to study the functional role of PDI in parasite infection and the interaction between macrophage PDI and?L. chagasi
- in the in vitro translation reaction for the generation of disulfide bonds
- in insulin-disulfide reduction assay and peptide binding assay
- as a positive control in thiol-disulfide oxidoreductase activity assay
| [General Description]
Protein disulfide isomerase (PDI) from bovine liver is a homodimer with a molecular weight of 107 kDa with the monomer corresponding to 57 kDa. The isoelectric point (pI) is approximately 4.2. The enzyme is a glycoprotein with 12% total carbohydrate content comprising of mannose, galactose, N-acetyl neuraminic acid (NANA) and 2-acetamido-2-deoxyglucose. PDI is an ubiquitous redox chaperone enzyme. It belongs to the, thioredoxin superfamily and is high conserved. | [Biochem/physiol Actions]
Protein Disulfide Isomerase (PDI) is mainly located in the endoplasmic reticulum (ER), where it assists in protein-folding and thiol-disulfide exchanges. It aids protein refolding in vitro allowing recombinant proteins to achieve their native state. |
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Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
Website: |
https://www.sigmaaldrich.cn |
Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
Company Name: |
Creative Enzymes
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Tel: |
1-516-855-7709 |
Website: |
www.creative-enzymes.com |
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