| Identification | Back Directory | [Name]
Albiflorin | [CAS]
39011-90-0 | [Synonyms]
ALBIFLORIN
Alibiflorin
ALBIFLORIN(P)
Albiflorin std
Albiflorin, >98%
Albiflorin USP/EP/BP
Albiflorin 39011-90-0
Paeonia lactiflora Pall.
Albiflorin, froM Paeonia lactiflora
4-hydroxy-6-methyl-, (1R, 3R, 4R, 6S)-
7-Oxatricyclo [4.3.0.03,9] nonan-8-one, 9-
Albiflorin, 98%, from Paeonia lactiflora Pall.
[(benzoyloxy)methyl]-1-(β-D-glucopyranosyloxy)-
9-((Benzoyloxy)methyl)-1-(β-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclononan-8-one
9-((Benzoyloxy)methyl)-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclononan-8-one
Albiflorin
9-((Benzoyloxy)methyl)-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclononan-8-one
(1R,3R,4R,6S,9S)-9-[(Benzoyloxy)Methyl]-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-Methyl-7-oxatricyclo[4.3.0.03,9]nonan-8-one
7-Oxatricyclo[4.3.0.03,9]nonan-8-one, 9-[(benzoyloxy)methyl]-1-(β-D-glucopyranosyloxy)-4-hydroxy-6-methyl-, (1R,3R,4R,6S,9S)- | [Molecular Formula]
C23H28O11 | [MDL Number]
MFCD00238531 | [MOL File]
39011-90-0.mol | [Molecular Weight]
480.46 |
| Chemical Properties | Back Directory | [Boiling point ]
722.1±60.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [storage temp. ]
?20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
powder | [pka]
12.84±0.70(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Definition]
ChEBI: Albiflorin is a monoterpene glycoside with formula C23H28O11, originally isolated from the roots of Paeonia lactiflora. It has a role as a plant metabolite and a neuroprotective agent. It is a benzoate ester, a gamma-lactone, a beta-D-glucoside, a monoterpene glycoside, a secondary alcohol and a bridged compound. | [Biological Functions]
Albiflorin is a natural product isolated from Paeoniae Radix. It enhances mitochondrial function to suppress antimycin A-induced oxidative damage via the preservation of cytochrome c and cardiolipin. Also it may reduce or prevent osteoblast degeneration in osteoporosis. | [Biological Activity]
Albiflorin is a natural phenolic compound that has been shown to be an inhibitor of toll-like receptor (TLR) 4. | [in vitro]
Albiflorin can modulate the TLR-induced inflammatory response by inhibiting the production of proinflammatory cytokines, such as IL-6, IL-8, and TNF-α. This compound also inhibits matrix metalloproteinase activity in tubulointerstitial injury, leading to decreased interstitial inflammation and proteinuria. Albiflorin has been shown to be effective at low doses in experimental models of rheumatoid arthritis. It is believed that this effect may be due to its ability to inhibit TLR4 expression or activation. |
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