| Identification | More | [Name]
2-IODOPHENYLACETONITRILE | [CAS]
40400-15-5 | [Synonyms]
2-IODOBENZYL CYANIDE
2-IODOPHENYLACETONITRILE
O-IODOPHENYLACETONITRILE
2-Iodophenylacetonitrile,96%
2-Iodobenzeneacetonitrile | [Molecular Formula]
C8H6IN | [MDL Number]
MFCD00040888 | [Molecular Weight]
243.04 | [MOL File]
40400-15-5.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
3276 | [WGK Germany ]
3
| [HazardClass ]
6.1 | [PackingGroup ]
III |
| Hazard Information | Back Directory | [Uses]
2-Iodophenylacetonitrile may be used in the preparation of:
- 2?-aminobiphen-2-ylacetonitrile
- ethyl (2-iodophenyl)iminoacetate hydrochloride
- 3,4-disubstituted 2-naphthalenamines
It may also be used in the preparation of the following nitriles:
- 2-(2-iodophenyl)-2-methylpropanenitrile
- 1-(2-iodophenyl)cyclopentanecarbonitrile
- 5-bromo-2-(2-iodophenyl)pentanenitrile
- 2-(2-iodophenyl)-2-propylpentanenitrile
- 1-(2-iodophenyl)cyclohexanecarbonitrile
- 1-(2-Iodophenyl)cyclopropanecarbonitrile
| [General Description]
2-Iodophenylacetonitrile is a 2-aryl substituted nitrile. It reacts with lactams to form ring-fused isoquinolinones via palladium-catalyzed carboxamidation in tandem with aldol condensation. |
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