ChemicalBook--->CAS DataBase List--->4146-30-9

4146-30-9

4146-30-9 Structure

4146-30-9 Structure
IdentificationMore
[Name]

Framycetin sulphate
[CAS]

4146-30-9
[Synonyms]

Framycetin Sulfate
NeomycinBsulfate
D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1?3)-O-.beta.-D-ribofuranosyl-(1?5)-O-2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1?4)-2-deoxy-, sulfate (1:3) (salt)
NEOMYCIN SULPHATE B(FRAMYCETIN SULPHATE)
Neomycin sulphate B
(2R,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2R,3R,4S,5R)-4-[(2S,3S,4S,5R,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxy-oxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxy-cyclohexyl]oxy-oxane-3,4-diol sulphate
Framycetin sulphate
4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine/sulfuric acid,(1:3)
[EINECS(EC#)]

223-969-3
[Molecular Formula]

C23H46N6O13.3H2O4S
[MDL Number]

MFCD00144873
[Molecular Weight]

712.72
[MOL File]

4146-30-9.mol
Chemical PropertiesBack Directory
[Appearance]

White or yellowish-white powder, hygroscopic.
[Melting point ]

>160°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Freely soluble in water, very slightly soluble in alcohol, practically insoluble in acetone.
[form ]

Solid
[color ]

White to Off-White
[Water Solubility ]

Water : 250 mg/mL (275.06 mM; Need ultrasonic)
[Stability:]

Hygroscopic
[Uses]

Antibacterial
[CAS DataBase Reference]

4146-30-9(CAS DataBase Reference)
Hazard InformationBack Directory
[Chemical Properties]

White or yellowish-white powder, hygroscopic.
[Originator]

Myciguent,Upjohn,US,1951
[Manufacturing Process]

Neomycin has been produced by growing the organism, Strepromyces No. 3535, in a suitable nutrient medium under appropriate stationary or submerged aerobic (viz shaken) conditions, and then isolating and purifying the substance, e.g., by procedure of the sort described in the figure including various steps of adsorption, recovery by elution, separation from impurities, and precipitation.
Neomycin is usually used as the sulfate.
[Therapeutic Function]

Antibacterial
Spectrum DetailBack Directory
[Spectrum Detail]

Framycetin sulphate(4146-30-9)1HNMR
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