| Identification | More | [Name]
2-Amino-5-fluorobenzoic acid | [CAS]
446-08-2 | [Synonyms]
2-AMINO-5-FLUOROBENZOIC ACID
5-FAA
5-FLUOROANTHRANILIC ACID
AURORA KA-5382
BUTTPARK 19\04-54
RARECHEM AL BO 2236
5-FluoroanthranilicAcid/2-Amino-5-FluorobenzoicAcid
2-Amino-5-fluoroBenzoicacid97.
2-Amino-5-fluorobenzoic Acid, 5-FAA
2-Amino-5-fluorobenzoic
2-Amino-5-fluorobenzoic acid 97.5%
2-AMINO-5-FLUOROBENZOIC ACID 99+%
5-FLUOROANTHRANILIC ACID 98+%
2-Amino-5-fluorobenzoic acid (5-Fluoroanthranilic acid)
2-Amino-5-fluorobenzoic acid, 98+%
5-Fluoroanthanilic acid | [EINECS(EC#)]
207-159-7 | [Molecular Formula]
C7H6FNO2 | [MDL Number]
MFCD00055566 | [Molecular Weight]
155.13 | [MOL File]
446-08-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
181-183 °C(lit.)
| [Boiling point ]
223.67°C (rough estimate) | [density ]
1.3021 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Fine Crystalline Powder | [pka]
1.86±0.10(Predicted) | [color ]
Light yellow to light brown | [Usage]
Used for the counterselection of TRP1, a commonly used genetic marker in the yeast Saccharoyces Cerevisiae. An antimetabolite for the tryptophan pathway in yeast, and is toxic by virtue of its antimetabolite conversion to 5-Fluorotryptophan. It ca | [BRN ]
2803664 | [InChI]
InChI=1S/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11) | [InChIKey]
FPQMGQZTBWIHDN-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC(F)=CC=C1N | [CAS DataBase Reference]
446-08-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29224900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
2-Amino-5-fluorobenzoic acid is used for the counterselection of TRP1, a commonly used genetic marker in the yeast Saccharoyces Cerevisiae. An antimetabolite for the tryptophan pathway in yeast, and is toxic by virtue of its antimetabolite conversion to 5-Fluorotryptophan. It can be used for the selection of tryptophan auxotroophs.
| [Definition]
ChEBI: An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 5 on the phenyl ring is replaced by fluorine. | [reaction suitability]
reaction type: solution phase peptide synthesis |
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