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524-63-0

524-63-0 Structure

524-63-0 Structure
IdentificationBack Directory
[Name]

cupreine
[CAS]

524-63-0
[Synonyms]

C06530
cupreine
Ultraquinine
O-Demethylquinidine
O-Desmethyl Quinine
6'-hydroxycinchonidine
(8,9R)-9-Diol Cinchonan-6’
(8α,9R)-Cinchonan-6',9-diol
(8,9R)-9-Diol Cinchonan-6 Cupreine
[EINECS(EC#)]

208-363-9
[Molecular Formula]

C19H22N2O2
[MDL Number]

MFCD09842542
[MOL File]

524-63-0.mol
[Molecular Weight]

310.395
Chemical PropertiesBack Directory
[Definition]

One of the cinchona alkaloids.
[Melting point ]

>171°C (dec.)
[alpha ]

D17 -176°
[Boiling point ]

450.55°C (rough estimate)
[density ]

1.1396 (rough estimate)
[refractive index ]

1.5600 (estimate)
[storage temp. ]

-20?C Freezer
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

6.57(at 25℃)
[color ]

Off-White to Pale Yellow
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Solid
[Uses]

A metabolite of Quinine (Q694000).
[Purification Methods]

Cupreine crystallises from EtOH (anhydrous crystals) and wet Et2O (as dihydrate crystals). It has Kb 2.7x10-7 [Kolthoff Biochem Z 162 323]. The sulfate forms needles, m 257o(dec), from MeOH, amyl alcohol or H2O, with [] 20-197.9o (c 1.2, H2O). [Beilstein 22 I 165, 22 II 416.]
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