| Identification | More | [Name]
6-Methoxyisoquinoline | [CAS]
52986-70-6 | [Synonyms]
6-METHOXY-ISOQUINOLINE
6-Methoxyisoquinoline 90% | [Molecular Formula]
C10H9NO | [MDL Number]
MFCD04114861 | [Molecular Weight]
159.18 | [MOL File]
52986-70-6.mol |
| Hazard Information | Back Directory | [Chemical Properties]
Clear Oil | [Uses]
6-Methoxy Isoquinoline (cas# 52986-70-6) is a compound useful in organic synthesis. | [Preparation]
6-Methoxyisoquinoline synthesis: Using benzaldehyde as the starting material, m-methoxybenzaldehyde is obtained through nitration, reduction, diazotization, hydrolysis and methylation, and 3-methoxybenzaldehyde is obtained through condensation with nitromethane Shiff base and reduction of aluminum hydride -p-Phenylethylamine. The Pictet-Spengler reaction of 3-methoxyl-p-phenylethylamine and 40% aqueous formaldehyde produces 6-methoxyl-1,2,3,4-tetrahydroisoquinoline, and then obtains the target compound in dehydrogenation 6-Methoxyisoquinoline. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 69, p. 1939, 1947 DOI: 10.1021/ja01200a028 |
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