| Identification | Back Directory | [Name]
N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE | [CAS]
53774-63-3 | [Synonyms]
H-LYS(ACETIMIDOYL)-OH
LYSINE(ACETIMIDOYL)-OH
H-LYS(1-IMINOETHYL)-OH
Ne-Acetimidoyl-L-lysine
N-ε-Acetimidoyl-L-lysine
N-(5-Amino-5-carboxypentyl
L-Lysine, N6-(1-iMinoethyl)-
N-EPSILON-ACETIMIDOYL-L-LYSINE
N-EPSILON-ACETIMIDOYL-L-LYSIN-EPSILON
N-(5-AMINO-5-CARBOXYPENTYL)-ACETAMIDINE
N-(5-AMino-5-carboxypentyl)-acetaMidine, H-Lys(1-iMinoethyl)-OH, L-NIL | [Molecular Formula]
C8H17N3O2 | [MDL Number]
MFCD00792818 | [MOL File]
53774-63-3.mol | [Molecular Weight]
187.24 |
| Chemical Properties | Back Directory | [Boiling point ]
335.2±52.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [storage temp. ]
-15°C
| [solubility ]
Water: 50 mg/mL (267.04 mM); DMSO: < 1 mg/mL (insoluble or slightly soluble) | [form ]
Solid | [pka]
2.52±0.24(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
L-NIL is an inhibitor of inducible nitric oxide synthase (iNOS) with an IC50 value of 3.3 μM for miNOS. | [in vitro]
L-NIL produces a concentration-dependent inhibition of both the mouse inducible NOS (miNOS) and the rat brain constitutive NOS (rcNOS) and is considerably more potent for miNOS. The IC 50 values for L-NIL with miNOS and rcNOS are 3.3 and 92 pM, respectively, indicating that it is 28-fold more selective for miNOS. In addition, L-NIL has approximately 6-fold greater potency for miNOS than either L -NMA or L-NNA. | [target]
IC50: 3.3 μM (mouse inducible NO synthase), 92 μM (rat brain constitutive NO synthase) | [storage]
Store at -20°C |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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