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ChemicalBook--->CAS DataBase List--->54472-66-1

54472-66-1

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54472-66-1 Structure

54472-66-1 Structure
IdentificationBack Directory
[Name]

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
[CAS]

54472-66-1
[Synonyms]

GHIH
SOMATOSTATIN 14, ACETATE
Somatostatin monoacetate
AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT
[Molecular Formula]

C78H108N18O21S2
[MDL Number]

MFCD08459563
[MOL File]

54472-66-1.mol
[Molecular Weight]

1697.95
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Water: 0.3 mg/ml
[form ]

A powder
Hazard InformationBack Directory
[Description]

Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.
[storage]

Store at -20°C
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