| Identification | Back Directory | [Name]
LEUPEPTIN HEMISULFATE MONOHYDRATE | [CAS]
55123-66-5 | [Synonyms]
Gentibiose
methyl-(s)-
l-valeramide
β-Gentiobiose,β-form
AC-LEU-LEU-ARGINAL 1/2H2SO4 H2O
Ac-Leu-Leu-Arg-aldehyde . sulfate
LEUPEPTIN HEMISULFATE MONOHYDRATE
6-O-?D-Glucopyranosyl-D-glucopyranose
Ac-Leu-Leu-Arg-aldehyde · sulfate salt
6-O-B-D-GLUCOPYRANOSYL-D-GLUCOPYRANOSE
(2S)-2-[(Ac-Leu-Leu-)Amino]-5-guanidinopentanal
(S)-2-[(N-Acetyl-L-Leu-L-Leu-)amino]-5-guanidinopentanal
ACETYL-L-LEUCYL-L-LEUCYL-L-ARGININAL HEMISULFATE MONOHYDRATE
(2S)-5-Guanidino-2-[[N-(N-acetyl-L-leucyl)-L-leucyl]amino]pentanal
(s)-2-(2-acetamido-4-methylvaleramido)-n-(1-formyl-4-guanidinobutyl)-4-methy
L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-
(2S)-2-[[(2S)-2-acetamido-4-methyl-pentanoyl]amino]-N-[(1S)-1-formyl-4-guanidino-butyl]-4-methyl-valeramide
(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
(2S)-2-[[(2S)-2-acetamido-4-methyl-pentanoyl]amino]-N-[(2S)-5-[bis(azanyl)methylideneamino]-1-oxo-pentan-2-yl]-4-methyl-pentanamide | [Molecular Formula]
C20H38N6O4 | [MDL Number]
MFCD00198027 | [MOL File]
55123-66-5.mol | [Molecular Weight]
426.55 |
| Chemical Properties | Back Directory | [Boiling point ]
541.98°C (rough estimate) | [density ]
1.1865 (rough estimate) | [refractive index ]
1.6000 (estimate) | [RTECS ]
YV4205100 | [form ]
Powder | [pka]
13.44±0.46(Predicted) |
| Hazard Information | Back Directory | [Definition]
ChEBI: Leupeptin is a tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death. It has a role as a serine protease inhibitor, a bacterial metabolite, a cathepsin B inhibitor, a calpain inhibitor and an EC 3.4.21.4 (trypsin) inhibitor. It is a tripeptide and an aldehyde. It is a conjugate base of a leupeptin(1+). | [Safety Profile]
Questionable carcinogen withexperimental neoplastigenic data. When heated todecomposition it emits toxic fumes of NOx. |
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