| Identification | More | [Name]
DIPROPYLENETRIAMINE | [CAS]
56-18-8 | [Synonyms]
3,3'-DIAMINODIPROPYLAMINE
3,3-DIAMINODIPROPYLAMINE
3,3'-IMINOBISPROPYLAMINE
3,3-IMINOBISPROPYLAMINE
3,3'-IMINODIPROPYLAMINE
BIS-(3-AMINOPROPYL)AMINE
DIPROPYLENETRIAMINE
IBPA
IMINO BIS PROPYLAMINE
IMINODIPROPYLAMINE
N-(3-AMINOPROPYL)-1,3-PROPANEDIAMINE
RARECHEM AL BW 0231
1,3-Propanediamine, N-(3-aminopropyl)-
1,7-Diamino-4-azaheptane
1-Propanamine, 3,3'-iminobis-
3,3’-diamino-dipropylamin
3,3’-iminobis-propylamin
3,3'-Iminopropylamine
-3-Aminopropyl
3-Propanediamine,N-(3-aminopropyl)-1 | [EINECS(EC#)]
200-261-2 | [Molecular Formula]
C6H17N3 | [MDL Number]
MFCD00008214 | [Molecular Weight]
131.22 | [MOL File]
56-18-8.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless to yellow liquid | [Melting point ]
−14 °C(lit.) | [Boiling point ]
151 °C50 mm Hg(lit.) | [density ]
0.938 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.481(lit.)
| [Fp ]
245 °F
| [storage temp. ]
2-8°C
| [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [Water Solubility ]
Completely miscible in water | [form ]
clear liquid | [pka]
pK1:8.02(＋2);pK2:9.70(＋1);pK3:10.70(0) (30°C) | [color ]
Colorless to Almost colorless | [Stability:]
Air and light sensitive. Combustible. Incompatible with oxidizing agents. | [BRN ]
1071254 | [LogP]
-0.826 (est) | [CAS DataBase Reference]
56-18-8(CAS DataBase Reference) | [EPA Substance Registry System]
Norspermidine (56-18-8) |
| Safety Data | Back Directory | [Hazard Codes ]
T+,C | [Risk Statements ]
R22:Harmful if swallowed.
R24:Toxic in contact with skin.
R26:Very Toxic by inhalation.
R35:Causes severe burns.
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2269 8/PG 3
| [WGK Germany ]
2
| [RTECS ]
JL9450000
| [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29252900 | [Safety Profile]
Poison by skin contact. Moderately toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NO,. An explosive |
| Hazard Information | Back Directory | [General Description]
A colorless liquid. Less dense than water. Flash point of 170°F. Very irritating to skin and eyes, and may be toxic by ingestion. Used to make soaps, dyes, and pharmaceuticals. | [Reactivity Profile]
3,3'-IMINODIPROPYLAMINE(56-18-8) neutralize acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. This compound can react with oxidizing materials . | [Air & Water Reactions]
Water soluble. | [Hazard]
Toxic by ingestion and inhalation; irritant. | [Health Hazard]
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. | [Fire Hazard]
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. | [Chemical Properties]
colourless to yellow liquid | [Uses]
Bis(3-aminopropyl)amine (BAPA) can be used:
- To synthesize chitosan based hydrogels having potential biomedical applications.
- For the functionalization of nanoparticles to yield terminal ?NH2 groups for further modifications.
- As an internal dispersing agent for the synthesis of water-dispersible polyurethanes.
- As a ligand in the preparation of [Cu(bapa)]2[Mo(CN)8]·7H2O photomagnetic coordination polymer.
| [Uses]
A structural homologue of the natural polyamine spermidine with antitumor activity that may make it useful as a antineoplastic agent. | [Definition]
ChEBI: Bis(3-aminopropyl)amine is a polyazaalkane. It has a role as an algal metabolite and a plant metabolite. It is a conjugate base of a bis(3-azaniumylpropyl)azanium. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 58, p. 3736, 1993 DOI: 10.1021/jo00066a028
Journal of the American Chemical Society, 105, p. 5002, 1983 DOI: 10.1021/ja00353a025 | [Purification Methods]
Dry the amine with Na and distil it under vacuum. [Beilstein 4 IV 1278.] |
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