| Identification | Back Directory | [Name]
L-Anserine | [CAS]
584-85-0 | [Synonyms]
Anserin
L-Anserine
H-β-Ala-His(3-Me)-OH
L-Histidine, β-alanyl-3-methyl-
beta-Alanyl-3-methyl-L-histidine
L-N-beta-Alanyl-3-methylhistidine
N-beta-alanyl-3-methyl-L-histidine
Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine
2-(3-aminopropanoylamino)-3-(3-methylimidazol-4-yl)-propanoic acid
(S)-2-(4-Aminobutanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
(S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-4-yl)propanoic acid
(S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
(2S)-2-[(3-ammonio-1-oxopropyl)amino]-3-(3-methyl-4-imidazolyl)propanoate | [EINECS(EC#)]
209-545-0 | [Molecular Formula]
C10H16N4O3 | [MDL Number]
MFCD11040910 | [MOL File]
584-85-0.mol | [Molecular Weight]
240.26 |
| Chemical Properties | Back Directory | [Melting point ]
268℃ (decomposition) | [Boiling point ]
611.3±55.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Methanol (Slightly, Heated), Water (Slightly) | [form ]
Solid | [pka]
3.02±0.10(Predicted) | [color ]
White to Off-White | [LogP]
-2.220 (est) |
| Hazard Information | Back Directory | [Definition]
ChEBI: Anserine is a dipeptide comprising of beta-alanine and 3-methyl-L-histidine units. It has a role as an animal metabolite and a mouse metabolite. It is a beta-alanine derivative and a dipeptide. It is a tautomer of an anserine zwitterion. | [storage]
Store at 4°C, protect from light | [Purification Methods]
Crystallise anserine from aqueous EtOH. It is hygroscopic and is best stored as the nitrate salt (see below). Purify it by shaking the nitrate salt with Dowex 3 (x4 free base) and washing with H2O, evaporating the filtrate and removing H2O by 3 distillations with 10mL of propan-2-ol. Dissolve the crystals in MeOH and add H2O dropwise until one phase is obtained and cool. Dry the crystals at 60o over P2O5 in a vacuum. The picrate has m 145o (from H2O). [Rinderknecht et al. J Org Chem 29 1968 1964, Beilstein 25 II 408, 25 IV 4383.] |
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