| Identification | Back Directory | [Name]
N1,N12-Diacetylspermine | [CAS]
61345-83-3 | [Synonyms]
N1,N12-Diacetylspermine
N,N'-Bis(3-acetylaminopropyl)-1,4-butanediamine
N-[3-[4-(3-acetamidopropylamino)butylamino]propyl]acetamide
Acetamide, N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis- | [Molecular Formula]
C14H30N4O2 | [MOL File]
61345-83-3.mol | [Molecular Weight]
286.41 |
| Hazard Information | Back Directory | [Uses]
N1,N12-Acetylspermine is a diacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. Upregulation of N1,N12-acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.[Cayman Chemical] | [Definition]
ChEBI:N(1),N(12)-diacetylspermine is an acetylspermine. It is a conjugate base of a N(1),N(12)-diacetylsperminium(2+). |
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