61345-83-3
61345-83-3 结构式
基本信息
英文别名
N1,N12-DiacetylspermineN,N'-Bis(3-acetylaminopropyl)-1,4-butanediamine
N-[3-[4-(3-acetamidopropylamino)butylamino]propyl]acetamide
Acetamide, N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis-
应用领域
用途一
N1,N12-Acetylspermine is a diacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. Upregulation of N1,N12-acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.[Cayman Chemical]