61837-65-8

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61837-65-8 Structure

Identification	Back Directory
[Name] 4-HYDROXY MEPHENYTOIN
[CAS] 61837-65-8
[Synonyms] 4-HYDROXY MEPHENYTOIN 4'-Hydroxymephenitoyn (+/-) -HYDROXYMEPHENYTOIN (+/-)-4-HYDROXYMEPHENYTOIN 4-HydroxyMephenytoin >=98% (HPLC) 5-Ethyl-5-(4-hydroxyphenyl)-3-Methyl- 5-Ethyl-3-methyl-5-(4-hydroxyphenyl)hydantoin (+/-)-5-ETHYL-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN (+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN 4-Hydroxy-5-ethyl-3-methyl-5-phenylimidazolidin-2-one 5-Ethyl-3-methyl-5-(4-hydroxyphenyl)imidazolidine-2,4-dione 5-ethyl-5-(4-hydroxyphenyl)-3-MethyliMidazolidine-2,4-dione 5-(p-Hydroxyphenyl)-3-methyl-5-ethyl-imidazolidine-2,4-dione (+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLIMIDIDAZOLIDINE-2,4-DIONE (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin, (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione
[Molecular Formula] C12H14N2O3
[MDL Number] MFCD00142316
[MOL File] 61837-65-8.mol
[Molecular Weight] 234.25

Hazard Information	Back Directory
[Chemical Properties] White Solid
[Uses] CYP2C19 metabolite of Mephenytoin
[Uses] Pharmacological activity investigating:• ;The drug effects on metabolization1• ;In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3
[Definition] ChEBI: Hydroxymephenytoin is an imidazolidine-2,4-dione.
[General Description] CYP2C19 metabolite of mephenytoin.
[Biochem/physiol Actions] 4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized.

Safety Data	Back Directory
[WGK Germany ] 3

Spectrum Detail	Back Directory
[Spectrum Detail] 4-HYDROXY MEPHENYTOIN(61837-65-8)¹HNMR

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