| Identification | Back Directory | [Name]
CONGLOBATIN | [CAS]
72263-05-9 | [Synonyms]
FW-04-806
CONGLOBATIN
Conglobatin, >=99%
(3E,5R,7S,8S,11E,13R,15S,16S)-3,5,7,11,13,15-Hexamethyl-8,16-bis(5-oxazolylmethyl)-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
1,9-Dioxacyclohexadeca-3,11-diene-2,10-dione, 3,5,7,11,13,15-hexamethyl-8,16-bis(5-oxazolylmethyl)-, (3E,5R,7S,8S,11E,13R,15S,16S)- | [Molecular Formula]
C28H38N2O6 | [MDL Number]
MFCD01730317 | [MOL File]
72263-05-9.mol | [Molecular Weight]
498.61 |
| Chemical Properties | Back Directory | [density ]
1.060±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
-20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
White to off-white solid. |
| Hazard Information | Back Directory | [Uses]
Isolated from Streptomyces conglobatus, conglobatin has a unusual, dimeric, macrolide dilactone structure with pendant oxazole groups. Conglobatin exhibits an IC50 of 0.63 μg/ml in a NFAT-dependant transcription assay. No toxicity was observed at doses up to 1000 mg/kg when administered to mice either orally or interperitoneally. | [storage]
Store at -20°C |
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