| Identification | Back Directory | [Name]
Darodipine | [CAS]
72803-02-2 | [Synonyms]
PY-108063
PY-108068
PY-108-068
Darodipine
Darodipine(PY-108068)
4-(Benzofurazan-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester
3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester | [Molecular Formula]
C19H21N3O5 | [MDL Number]
MFCD00867049 | [MOL File]
72803-02-2.mol | [Molecular Weight]
371.39 |
| Chemical Properties | Back Directory | [Melting point ]
148-151°C | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Pale Yellow to Light Yellow |
| Hazard Information | Back Directory | [Uses]
Antihypertensive; bronchodilator; vasodilator. | [in vivo]
Treatment with darodipine increases the number and the average length of alkaline phosphatase-reactive capillaries and reduces the intercapillary distance and the diameter of cerebral capillaries in old rats. The pericapillary microrenvironment of the Ammon’s horn is the most sensitive to treatment with darodipine[1]. Darodipine may reduce neuronal cytoskeletal changes occurring in aging and in neurodegenerative disorders. A 6-month treatment (from the 18th to the 24th month of life) with an oral daily dose of 10 mg/kg of darodipine restores in part the expression of 200 kDa-NF subunit immunoreactivity in the cerebellar cortex[2]. | [storage]
Store at -20°C |
|
| Company Name: |
sinopharm
|
| Tel: |
13856035343 |
| Website: |
www.sinopharm.ah.cn |
|