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7554-12-3

7554-12-3 Structure

7554-12-3 Structure
IdentificationBack Directory
[Name]

Diethyl malate
[CAS]

7554-12-3
[Synonyms]

FEMA 2374
DIETHYL MALATE
ETHYL-DL-MALATE
DIETHYL DL-MALATE
Malic acid diethyl
DiethylDL-Malate>
Diethyl hydroxysuccinate
Diethyl 2-hydroxysuccinate
DL-MALIC ACID DIETHYL ESTER
DL-APPLE ACID DIETHYL ESTER
DL-MALIC ACID DIETHYL ESTER 98+%
Diethyl DL-Malate
Hydroxysuccinic acid diethyl ester
hydroxy-butanedioicacidiethylester
Hydroxybutanedioic acid diethyl ester
2-hydroxy-butanedioicaciddiethylester
Butanedioicacid,hydroxy-,diethylester
Butanedioic acid, 2-hydroxy-, 1,4-diethyl ester
diethylmalate,hydroxy-butanedioicacid,diethylester
DL-Apple Acid Diethyl Ester DL-Malic Acid Diethyl Ester
[EINECS(EC#)]

231-444-5
[Molecular Formula]

C8H14O5
[MDL Number]

MFCD00048556
[MOL File]

7554-12-3.mol
[Molecular Weight]

190.19
Chemical PropertiesBack Directory
[Boiling point ]

122-124 °C12 mm Hg(lit.)
[density ]

1.128 g/mL at 25 °C(lit.)
[FEMA ]

2374 | DIETHYL MALATE
[refractive index ]

1.4330 to 1.4360
[Fp ]

185 °F
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Sparingly), Ethyl Acetate (Slightly)
[form ]

clear liquid
[pka]

12.35±0.20(Predicted)
[color ]

Colorless to Light yellow
[Odor]

at 100.00 %. brown sugar sweet wine fruity herbal
[Odor Type]

caramellic
[JECFA Number]

620
[Dielectric constant]

10.2(18℃)
[LogP]

0.23
[EPA Substance Registry System]

Butanedioic acid, hydroxy-, diethyl ester(7554-12-3)
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

2918.19.9000
Raw materials And Preparation ProductsBack Directory
[Raw materials]

L-Malic acid-->YSAVZVORKRDODB-UHFFFAOYSA-N-->Diethyl fumarate-->Water-->Levulinic acid-->Ethanol-->2-Methyltetrahydrofuran-->DL-Malic acid-->Furfural
Hazard InformationBack Directory
[Chemical Properties]

Diethyl malate has a fruity odor with a pleasant herbaceous undertone. It is an ester of dicarboxylic acid
[Occurrence]

It exhibits two optically active isomers in addition to the optically inactive form; the most common is the l-isomer; reported present in the cultures of certain fungi (Rhizopus). Reported found in raspberry, cognac, malt whiskey, cider, sherry, white, red, port, sparkling, rose, strawberry and bilberry wines
[Uses]

Diethyl DL-Malate is used as a reagent in the synthesis of dicarboxylic nitroxyalkylamides and nitroxyalkylimides as anti-ischemic agents.
[Definition]

ChEBI: Diethyl malate is a malate ester obtained by the formal condensation of the two carboxy groups of malic acid with two molecules of ethanol respectively. It has a role as a metabolite.
[Preparation]

The l-isomer can be prepared by esterification of the l-isomer of the acid with alcohol in the presence of HCl.
[Synthesis Reference(s)]

Synthesis, p. 138, 1982 DOI: 10.1055/s-1982-29718
Spectrum DetailBack Directory
[Spectrum Detail]

Diethyl malate(7554-12-3)1HNMR
Diethyl malate(7554-12-3)FT-IR
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