Identification | More | [Name]
HNE | [CAS]
75899-68-2 | [Synonyms]
HNE 4-HNE Ccris 1781 4-HYDROXYNONENAL 4-hydroxy-2-nonena 4-HYDROXY-2-NONENAL (E)-4-HYDROXYNONENAL (E)-4-hydroxynon-2-enal HNE ISO 9001:2015 REACH (+/-)-4-HYDROXYNON-2-ENAL (+/-)-4-HYDROXY-2E-NONENAL 2-Nonenal, 4-hydroxy-, (2E)- Mouse 4-Hydroxy-2-nonenal elisa kit | [Molecular Formula]
C9H16O2 | [MDL Number]
MFCD00211020 | [Molecular Weight]
156.22 | [MOL File]
75899-68-2.mol |
Chemical Properties | Back Directory | [Boiling point ]
125-127 °C(Press: 2 Torr) | [density ]
0.941±0.06 g/cm3(Predicted) | [storage temp. ]
-70°C | [solubility ]
DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml | [form ]
Colorless oil. | [pka]
13.31±0.20(Predicted) | [color ]
Colorless to light yellow | [CAS DataBase Reference]
75899-68-2(CAS DataBase Reference) |
Hazard Information | Back Directory | [Uses]
HNE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-hydroxy Nonenal is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. HNE inhibits pro-oxidant-induced Ca2+ release from mitochondria at 10-50 μM.[Cayman Chemical]
| [Definition]
ChEBI:4-hydroxynon-2-enal is an enal consisting of non-2-ene having an oxo group at the 1-position and a hydroxy group at the 4-position. It has a role as a human metabolite. It is a hydroxyaldehyde, an enal and a 4-hydroxynonenal. | [storage]
Store at -80°C,protect from light |
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