| Identification | More | [Name]
Diethyl phosphite | [CAS]
762-04-9 | [Synonyms]
AURORA KA-1208
DIETHYL HYDROGEN PHOSPHITE
Diethyl hydrogen phosphonate
DIETHYL PHOSPHITE
DIETHYL PHOSPHONATE
PHOSPHONIC ACID DIETHYL ESTER
PHOSPHOROUS ACID DIETHYL ESTER
Diethoxyphosphine oxide
Diethyl acid phosphite
diethylacidphosphite
diethylfosfit
Ethyl phosphonate ((EtO)2HPO)
Hydrogen diethyl phosphite
hydrogendiethylphosphite
O,O-Diethyl phosphonate
OPH(OC2H5)2
Diethylphosphitemincolorlessliq
DIETHYL PHOSPHITE, TECH., 94%
O,O"-DIETHYL PHOSPHITE
Diethylphosphite,min.95% | [EINECS(EC#)]
212-091-6 | [Molecular Formula]
C4H11O3P | [MDL Number]
MFCD00044573 | [Molecular Weight]
138.1 | [MOL File]
762-04-9.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Melting point ]
-70 °C | [Boiling point ]
50-51 °C/2 mmHg (lit.) | [density ]
1.072 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.407(lit.)
| [Fp ]
180 °F
| [form ]
Liquid | [color ]
Colorless | [Specific Gravity]
1.072 | [Stability:]
Stable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, strong bases. May decompose on exposure to moisture. Combustible. | [Water Solubility ]
miscible (hydrolysis) | [Hydrolytic Sensitivity]
7: reacts slowly with moisture/water | [Sensitive ]
Moisture Sensitive | [BRN ]
605759 | [InChIKey]
MJUJXFBTEFXVKU-UHFFFAOYSA-N | [CAS DataBase Reference]
762-04-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Phosphonic acid, diethyl ester(762-04-9) | [EPA Substance Registry System]
762-04-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S27:Take off immediately all contaminated clothing . | [WGK Germany ]
1
| [RTECS ]
TG7875000
| [F ]
10-13-21 | [TSCA ]
Yes | [HS Code ]
29209014 | [Hazardous Substances Data]
762-04-9(Hazardous Substances Data) |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Nitrogen-->Stirring vessel-->Oil pump | [Preparation Products]
(S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(R)-7,7'-BIS(DIPHENYLPHOSPHINO)-1,1'-SPIROBIINDANE-->Triethyl phosphite-->(R)-(+)-7,7'-BIS(DIPHENYLPHOSPHINO)-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(R)-(+)-7,7'-BIS[DI(4-METHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(S)-7,7'-Bis[di(p-methylphenyl)phosphino]-1,1'-spirobiindane ,97%-->4,4'-Vinylenedipyridine-->Iprobenfos-->(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL-->(R)-(+)-TolBINAP-->Diphenylphosphine oxide-->Fosetyl aluminum-->Foscarnet sodium-->Ethephon-->Diethyl chlorophosphate-->FOSAMINE AMMONIUM-->ETHYLPHOSPHONIC ACID-->Diethyl 3,5-di-tert-butyl-4-hydroxybenzyl phosphate-->PARAOXON-->DIETHYL PHOSPHATE-->Optical brightener OB-1-->SODIUM O,O-DIETHYLTHIOPHOSPHATE |
| Hazard Information | Back Directory | [Chemical Properties]
colourless liquid | [Definition]
ChEBI: A phosphonic ester that is the diethyl ester of phosphonic acid. | [Synthesis Reference(s)]
Synthetic Communications, 18, p. 665, 1988 DOI: 10.1080/00397918808077352 | [Synthesis Reference(s)]
Tetrahedron Letters, 29, p. 3327, 1988 DOI: 10.1016/0040-4039(88)85153-0 | [General Description]
Diethyl phosphite is reported to be chemical warfare agent (CWA) simulant, simulant for nerve agents sarin, soman, tabun, and VX. |
| Questions and Answers (Q&A) | Back Directory | [Uses]
Diethyl phosphite (DEPI) is a versatile reactive intermediate used in the production of various phosphorus based substances. It may be used to prepare the nickel chloride-diethyl phosphite system, efficient catalyst for the cross-coupling reaction between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides.
It may be used:
- in the stereoselective synthesis of β-fluorinated alkylphosphonates
- Used in synthesis of homoallylic bromide
- Used in synthesis of series of carbazole-based α-aminophosphonates
- used as an extraction agent and phosphate intermediate.
- Used in synthesis of pesticides kitazine and phosethyl-Al as well as synthetic O, O-diethyl phosphoryl chloride.
- used for the synthesis of plasticizers, flame retardants, etc.
- Diethyl phosphite is reported to be chemical warfare agent (CWA) simulant, simulant for nerve agents sarin, soman, tabun, and VX.
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