| Identification | More | [Name]
2-Nitrobenzenesulfenyl chloride | [CAS]
7669-54-7 | [Synonyms]
2-NITROBENZENESULFENYL CHLORIDE
2-NITROBENZENESULPHENYL CHLORIDE
2-NITROPHENYLSULFENYL CHLORIDE
NBSC
NPS-CL
NPS REAGENT
O-NITROBENZENESULFENYL CHLORIDE
o-nitrobenzenesulphenyl chloride
O-NITROPHENYLSULFENYL CHLORIDE
2-nitro-benzenesulfenylchlorid
2-Nitrophenylsulphenyl chloride
2-Nitrophenylsulfenyl Chloride [N-Protecting Agent for Peptides Research]
2-Nitrobenzenesulfenic acid chloride
(2-Nitrophenylthio) chloride
1-Nitro-2-(chlorothio)benzene
2-Nitrophenylchloro sulfide | [EINECS(EC#)]
231-644-2 | [Molecular Formula]
C6H4ClNO2S | [MDL Number]
MFCD00007128 | [Molecular Weight]
189.62 | [MOL File]
7669-54-7.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow to gold crystalline powder or needles | [Melting point ]
70-75 °C | [Boiling point ]
350.0±25.0 °C(Predicted) | [density ]
1.492 (estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
0-6°C | [form ]
Crystalline Powder or Needles | [color ]
Yellow to gold | [Water Solubility ]
decomposes | [Sensitive ]
Moisture Sensitive | [BRN ]
473741 | [CAS DataBase Reference]
7669-54-7(CAS DataBase Reference) | [EPA Substance Registry System]
7669-54-7(EPA Substance) |
| Questions And Answer(Q&A) | Back Directory | [Preparation]
CAUTION: This chloride is explosive, and the solvent has to be removed under reduced pressure.
To a 500-ml, three-necked flask equipped with a mechanical stirrer, thermometer, gas addition tube, and condenser is added 200 ml of dry carbon tetrachloride, 30 gm (0.1 mole) of 2,2'-dinitrophenyl disulfide, and 0.05 gm of iodine as a catalyst. The suspension is heated to 50-60°C, and chlorine gas is added at such a flow rate that 10 gm (0.14 mole) is added over a 2-2^-hr period at this temperature. After this time, the solid starting disulfide finally goes into solution, and the warm dark yellow solution is filtered. The solution is cooled to 5°C, and the product that crystallizes out is filtered and dried to afford 25.2-27.0 gm (66-71%), m.p. 73-74.5°C.
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| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S36/39:Wear suitable protective clothing and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
3261 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29309090 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow to gold crystalline powder or needles | [Uses]
2-Nitrobenzenesulfenyl Chloride is used in the synthesis of α-amino phosphonic acids | [Purification Methods]
Recrystallise it from CCl4 (2mL/g), filter off the solution at 5o (recovery 75%). It has also been recrystallised from pet ether (b 40-60o), dried rapidly at 50o and stored in a brown glass bottle, sealed well and stored away from moisture. [Hubacher Org Synth Coll Vol II 455 1943, Ito et al. Chem Pharm Bull Jpn 26 296 1978, Beilstein 6 I 157.] |
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