77303-64-1

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77303-64-1 Structure

Identification	Back Directory
[Name] Hydroxy-PEG4-CH2CO2Me
[CAS] 77303-64-1
[Synonyms] HO-PEG4-CH2COOMe Hydroxy-PEG4-CH2CO2Me Hydroxy-PEG4-methyl acetate 3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester HO-PEG4-CH2COOMe/3,6,9,12-Tetraoxatetradecanoic acid, 14-hydroxy-, methyl ester
[Molecular Formula] C11H22O7
[MDL Number] MFCD30828688
[MOL File] 77303-64-1.mol
[Molecular Weight] 266.29

Chemical Properties	Back Directory
[Boiling point ] 120 °C(Press: 0.001 Torr)
[density ] 1.125±0.06 g/cm3(Predicted)
[form ] Liquid
[pka] 14.36±0.10(Predicted)
[color ] Colorless to light yellow

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302-H315-H319-H335
[Precautionary statements ] P261-P305+P351+P338

Hazard Information	Back Directory
[Uses] Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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