| Identification | Back Directory | [Name]
DAGO | [CAS]
78123-71-4 | [Synonyms]
DAGO
DAMGO
Dagol
Damge
DAMPGO
RX-783006
NIH 10891
M.W. 513.59 C26H35N5O6
Tyr-D-Ala-Gly-MePhe-Gly-ol
H-Tyr-D-Ala(Me)Phe-NH-CH2-OH
TYR-D-ALA-GLY-N-ME-PHE-GLY-OL
2-Ala-4-mephe-5-Gly-enkephalin
Tyr-D-Ala-Gly-MePhe-NH-(CH2)2OH
H-Tyr-D-Ala-Gly-N-Me-Phe-Gly-OL
Tyr-D-Ala-Gly-(methyl)Phe-Gly-ol
H-TYR-D-ALA-GLY-N-ME-PHE-GLYCINOL
[D-Ala2,MePhe4,Gly-ol5]enkephalin
TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL
ala(2)-mephe(4)-gly-ol(5)-enkephali
(D-Ala2,N-Me-Phe4,Gly5-ol)enkephalin
Ala(2)-mephe(4)-Gly-ol(5) enkephalin
L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-Gly-OH
[D-ALA2, NME-PHE4, GLY-OL5]-ENKEPHALIN
[D-ALA2, N-ME-PHE4, GLY-OL]-ENKEPHALIN
Enkephalin, Ala(2)-mephe(4)-Gly-ol(5)-
(D-ALA2,N-ME-PHE4,GLYCINOL5)-ENKEPHALIN
[D-ALA2,N-METHYL-PHE4,GLY-OL5]-ENKEPHALIN
DAMGO >98% SYNTHETIC (D-ALA2,N-ME-PHE4,G LY
Tyr-D-Ala-Gly-N-methylphenylalanine-glycinol
3: PN: WO2009046859 PAGE: 98 claimed protein
PN: US20030176421 PAGE: 54-55 claimed protein
[D-Ala(2),N-methyl-Phe(4),Gly(5)-ol]-enkephalin
L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-N-(2-hydroxyethyl)-NH2
L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nα-methyl-
L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide | [Molecular Formula]
C26H35N5O6 | [MDL Number]
MFCD00076432 | [MOL File]
78123-71-4.mol | [Molecular Weight]
513.59 |
| Chemical Properties | Back Directory | [Boiling point ]
922.7±65.0 °C(Predicted) | [density ]
1.271±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [solubility ]
≥40.7 mg/mL in EtOH; ≥40.7 mg/mL in H2O; ≥42.2 mg/mL in DMSO | [form ]
solid | [pka]
9.97±0.15(Predicted) | [color ]
White | [Water Solubility ]
Soluble in water (4 mM) | [Sequence]
H-Tyr-D-Ala-Gly-NMe-Phe-Gly-ol | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
DAMGO is an opioid receptor agonist (1,2). DAMGO can be used to investigate the analgesic mechanism of opioids. It has been shown that DAMGO can modulate the two-pore domain K(+) channels in the substantia gelatinosa neurons (3). | [Definition]
ChEBI: (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin is a peptide. | [Biological Activity]
Highly selective peptide agonist for the μ opioid receptor. | [storage]
-20°C, protect from light |
|
|