| Identification | More | [Name]
N-Aminothiourea | [CAS]
79-19-6 | [Synonyms]
3-thiosemicarbazide
AKOS BBS-00004328
HYDRAZINECARBOTHIOAMIDE
LABOTEST-BB LT01593682
n-aminothiourea
THIOCARBAMOYL HYDRAZIDE
TSC
1-Amino-2-Thiourea
1-amino-2-thiourea(thiosemicarbazide)
1-Aminothiourea
2-Thiosemicarbazide
3-thio-semicarbazid
ai3-16319
Aminothiourea
aminothio-urea
Isothiosemicarbazide
Rcra waste number P116
rcrawastenumberp116
Semicarbazide, 3-thio-
Semicarbazide, thio- | [EINECS(EC#)]
201-184-7 | [Molecular Formula]
CH5N3S | [MDL Number]
MFCD00007620 | [Molecular Weight]
91.14 | [MOL File]
79-19-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Thiosemicarbazide is an odorless, white crystalline powder. | [Melting point ]
180-183 °C (dec.)(lit.)
| [Boiling point ]
208.6±23.0 °C(Predicted) | [density ]
1.221 (estimate) | [vapor pressure ]
1.15Pa at 25℃ | [refractive index ]
1.5800 (estimate) | [storage temp. ]
Poison room | [solubility ]
DMSO : 125 mg/mL (1371.52 mM; Need ultrasonic) | [form ]
Powder | [pka]
pK1:1.5(+1) (25°C,μ=0.1) | [color ]
White to light yellow | [PH]
5-7 (50g/l, H2O, 20℃) | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
soluble | [Merck ]
14,9361 | [BRN ]
506320 | [InChIKey]
BRWIZMBXBAOCCF-UHFFFAOYSA-N | [LogP]
-1.67 | [CAS DataBase Reference]
79-19-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Hydrazinecarbothioamide(79-19-6) | [EPA Substance Registry System]
79-19-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T+ | [Risk Statements ]
R28:Very Toxic if swallowed.
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 2811 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
VT4200000
| [F ]
8-9-23 | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29309070 | [HS Code ]
29335995 | [Safety Profile]
Poison by ingestion,
intraperitoneal, and intravenous routes.
Questionable carcinogen with experimental
tumorigenic data. Human mutation data
reported. When heated to decomposition it
emits very toxic fumes of NOx and SOx. | [Hazardous Substances Data]
79-19-6(Hazardous Substances Data) | [Toxicity]
LD50 orally in adult Norway rats: 13 mg/kg, Dieke, Proc. Soc. Exp. Biol. Med. 70, 688 (1949) |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Thiourea-->Ammonium thiocyanate-->Hydrazine sulfate | [Preparation Products]
CEFTRIAXONE-->2-Chloropyrimidine-4-carboxylic acid-->Robenidine hydrochloride-->BISMERTHIAZOL-->5-amino-1,3,4-thiadiazole-2-carboxylic acid-->CAFENSTROLE-->5-AMINO-1,3,4-THIADIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER-->AZIDITHION-->1,2,3,4-THIATRIAZOL-5-AMINE-->3-tert-butyl-1H-1,2,4-triazole-5-thiol-->Rubber auxiliary-->2-tirfluoromethylpyridine-->1H-1,2,4-Triazole-3-thiol-->2-Amino-5-methyl-1,3,4-thiadiazole-->4-thiadiazole,2-amino-5-pentyl-3-->ETHYL 1-(4-PHENYL-1,3-THIAZOL-2-YL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE |
| Hazard Information | Back Directory | [General Description]
THIOSEMICARBAZIDE(79-19-6) is a white crystalline powder and is odorless. This material is used as a reagent for ketones and certain metals, for photography and as a rodenticide. THIOSEMICARBAZIDE(79-19-6) is also effective for control of bacterial leaf blight of rice. Not a registered pesticide in the U.S. THIOSEMICARBAZIDE(79-19-6) is a chemical intermediate for herbicides and a reagent for detection of metals. | [Reactivity Profile]
Isocyanates and thioisocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)]. | [Health Hazard]
This material is highly toxic by ingestion. May induce goiter and cause delayed toxic effects in blood and skin. May be mutagenic in human cells. | [Potential Exposure]
Thiosemicarbazide is a dithiocarbamide compound is used as an intermedialte for pharmaceuticals and herbicides; as a reagent for ketones and certain metals; in certain photography and dye operations; as a rodenticide. It is also effective for control of bacterial leaf blight of rice. | [Fire Hazard]
When heated to decomposition, very toxic fumes of sulfur oxides and nitrogen oxides are emitted. | [First aid]
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Speed in removing material from skin is of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. | [Shipping]
UN2771 Thiosemicarbazide, pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. | [Incompatibilities]
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.) and strong reducing agents; contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. May react with nitrates. | [Chemical Properties]
Thiosemicarbazide is an odorless, white crystalline powder. | [Chemical Properties]
white crystalline solid | [Uses]
As a reagent for detection of metals. | [Definition]
ChEBI: Hydrazinecarbothioamide is a member of the class of thioureas that is thiourea in which a hydrogen of one of the amino groups is replaced by an amino group. It is a member of hydrazines, a thiocarboxamide and a member of thioureas. | [Flammability and Explosibility]
Nonflammable | [storage]
Store at -20°C | [Purification Methods]
Crystallise thiosemicarbazide from H2O (solubility is 20.3% w/w at 80o). The hydrochloride has m 190-191o(dec, 184o also reported). It forms salts with heavy metals. [Beilstein 3 H 195, 3 I 79, 3 II 134, 3 III 315, 3 IV 374.] |
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