| Identification | More | [Name]
Loxoprofen sodium | [CAS]
80382-23-6 | [Synonyms]
LOXOPROFEN SODIUM
sodium 2-[4-(2-oxocyclopentyl-1-methyl)phenyl]propionate dihydrate
alpha-methyl-4-((2-oxocyclopentyl)methyl)benzeneacetatesodiumsaltdihydrate
benzeneaceticacid,alpha-methyl-4-((2-oxocyclopentyl)methyl)-,sodiumsalt,di
cs-600
loxoprofensodium(patented-nosupply)
loxoprofensodiumdihydrate
sodium2-(4-(2-oxocyclopentylmethyl)phenyl)propionatedihydrate
LOXOPROFEN NA
MONOSODIUM2-[4-(2-OXOCYCLOPENTYLMETHYL)PHENYL]PROPANOATEDIHYDRATE(LOXOPROFENSODIUM)
Benzeneacetic acid, a-methyl-4-[(2-oxocyclopentyl)methyl]-, sodium salt (9CI)
CS 600 (antiinflammatory)
Loxonin
Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate
2-[p-(2-Oxocyclopentylmethyl)phenyl]propionic acid sodium salt
Unastin
α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid sodium salt | [EINECS(EC#)]
1806241-263-5 | [Molecular Formula]
C15H17NaO3 | [MDL Number]
MFCD00941425 | [Molecular Weight]
268.28 | [MOL File]
80382-23-6.mol |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO: soluble | [form ]
A solid | [color ]
White to off-white | [InChI]
InChI=1S/C15H18O3.Na.H/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);; | [InChIKey]
ALZXNWUYLUBHJL-UHFFFAOYSA-N | [SMILES]
C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1.[NaH] | [CAS DataBase Reference]
80382-23-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Loxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity. | [Originator]
Sankyo (Japan) | [Uses]
anti-inflammatory | [Definition]
ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration. | [Brand name]
LOXONIN | [Mechanism of action]
As most NSAIDs, loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. | [Side effects]
Adverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation. |
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