| Identification | Back Directory | [Name]
1,4-O-DidesMethyl rac-Niranthin | [CAS]
81263-83-4 | [Synonyms]
WTRAXKOXNKPSLF-IRXDYDNUSA-N
1,4-O-DidesMethyl rac-Niranthin | [Molecular Formula]
C22H28O7 | [MDL Number]
MFCD31563658 | [MOL File]
81263-83-4.mol | [Molecular Weight]
404.45 |
| Hazard Information | Back Directory | [Uses]
1,4-O-Didesmethyl rac-Niranthin is an intermediate in the synthesis of rac-Niranthin (N481000), a lignan compound isolated from the plant Phyllanthus amarus and shows anti-leishmanial activity. It acts through induction of topoisomerase I-mediated DNA-protein adduct formation in Leishmania cells triggering apoptosis of cellular nucleases. It also maintains the ability to reduce uric acid concentrations through xanthine oxidase inhibition. |
|
|