| Identification | Back Directory | [Name]
Gastric Mucin | [CAS]
84082-64-4 | [Synonyms]
MUCIN
Gastron
MUCIN TYPE I
MUCIN TYPE II
MUCIN GASTRIC
Gastric Mucin
Mutin(gastric)
MUCIN TYPE III
MUCIN TYPE I-S
Mucins, gastric
MUCIN,CRUDE,TYPEII
Mucin from porcine
MUCIN, GASTRIC, HOG
GASTRIC MUCIN PORCINE
Gastric Mucin USP/EP/BP
mucin from porcine stomach
EleMent of gastric Mucous MeMbrane
MUCIN FROM PORCINE STOMACH, TYPE III | [EINECS(EC#)]
282-010-7 | [Molecular Formula]
NULL | [MDL Number]
MFCD00131629 |
| Hazard Information | Back Directory | [Description]
Mucins are high-molecular-weight glycoproteins expressed throughout the gastrointestinal tract, with a key role in mucosal protection and function. In gastric cancer expression of MUC5AC and MUC1 is reduced and denovo expression of MUC2 occurs. | [Uses]
Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa. | [General Description]
Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli. | [Biological Activity]
Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin-17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. | [Biochem/physiol Actions]
Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells. |
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