Identification | More | [Name]
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid | [CAS]
86393-33-1 | [Synonyms]
1-CYCLOPROPYL-6-FLUORO-7-CHLORO-1,4-DIHYDRO-4-OXO-3-QUINOLINIC CARBOXYLIC ACID 1-CYCLOPROPYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLONE-3-CARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUOROQUINOL-4-ONE-3-CARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOQUINOLINE-3-CARBOXYLIC ACID 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXYHYDROQUINOLINE-3-CARBOXYLIC ACID 7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID 7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID AKOS 1131 Q-ACID Q-ACID, 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID TIMTEC-BB SBB003016 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylicaci 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylicacid 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-oxoquinoline-3-Carboxylate 1-Ciprofloxacin 7-CHLORO1-CYCLOPROPYL-6-FLUORO-1,4-DIHYD | [EINECS(EC#)]
405-050-0 | [Molecular Formula]
C13H9ClFNO3 | [MDL Number]
MFCD00792458 | [Molecular Weight]
281.67 | [MOL File]
86393-33-1.mol |
Chemical Properties | Back Directory | [Appearance]
Off-White Crystalline Powder | [Melting point ]
242-245 °C(lit.)
| [Boiling point ]
467.3±45.0 °C(Predicted) | [density ]
1.652±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
neat | [pka]
6.36±0.41(Predicted) | [color ]
Off-White to Light Yellow | [Usage]
An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial | [InChIKey]
ISPVACVJFUIDPD-UHFFFAOYSA-N | [CAS DataBase Reference]
86393-33-1(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S61:Avoid release to the environment. Refer to special instructions safety data sheet . S22:Do not breathe dust . | [WGK Germany ]
2
| [RTECS ]
VB1993795
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29334900 |
Hazard Information | Back Directory | [Chemical Properties]
Off-White Crystalline Powder | [Uses]
A metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial. | [Uses]
An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial | [General Description]
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug. |
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