| Identification | More | [Name]
2-Pyridinecarbaldehyde oxime | [CAS]
873-69-8 | [Synonyms]
2-PICOLINALDOXIME
2-PYRIDINEALDOXIME
2-PYRIDINECARBALDEHYDE OXIME
2-PYRIDINECARBOXALDEHYDE OXIME
PICOLINE ALDOXIME
PYRIDINE-2-ALDOXIME
PYRIDINE-2-CARBALDOXIME
PYRIDINE-2-CARBOXALDOXIME
SYM-2-PYRIDINEALDOXIME
TIMTEC-BB SBB004284
.alpha.-picolinealdoxime
2-Formylpyridine ketoxime
2-Formylpyridine oxime
2-Formylpyridineketoxime
2-Formylpyridineoxime
2-Hydroxyiminomethyl pyridine
2-Hydroxyiminomethylpyridine
2-Pyridinaldoxime
2-Pyridinecarboxaldoxime
2-Pyridylaldoxime | [EINECS(EC#)]
212-849-6 | [Molecular Formula]
C6H6N2O | [MDL Number]
MFCD00006354 | [Molecular Weight]
122.12 | [MOL File]
873-69-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
110-112 °C(lit.)
| [Boiling point ]
227.52°C (rough estimate) | [bulk density]
400-500kg/m3 | [density ]
1.2236 (rough estimate) | [vapor pressure ]
0.02-0.041Pa at 20-25℃ | [refractive index ]
1.4738 (estimate) | [storage temp. ]
Store below +30°C. | [solubility ]
methanol: 0.1 g/mL, clear
| [form ]
Solid | [pka]
pK1: 3.42(+1);pK2: 10.22(0) (25°C) | [color ]
Off-White | [PH]
7 (20°C, 13g/L in H2O) | [Water Solubility ]
15 g/L (20 ºC) | [BRN ]
109061 | [LogP]
0.3 at 25℃ | [CAS DataBase Reference]
873-69-8(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Pyridinealdoxime(873-69-8) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/22:Harmful by inhalation and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
TJ4180000 | [Hazard Note ]
Irritant | [HS Code ]
29333999 | [Toxicity]
LD50 intraperitoneal in mouse: 200mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
syn-2-Pyridinealdoxime is a 2-substituted pyridine derivative with inhibitory activity against prolyl-4-hydroxylase. syn-2-Pyridinealdoxime is used in the preparation of DNA-binding silver nitrate complexes. syn-2-Pyridinealdoximeis the N-demethylated analogue of AChE inhibitor Pralidoxime (P701120). | [Purification Methods]
Recrystallise it from Et2O/pet ether or H2O. The picrate has m 169-171o (from aqueous EtOH). It is used in peptide synthesis. [UV: Grammaticakis Bull Chem Soc Fr 109, 116 1956, Ginsberg & Wilson J Am Chem Soc 79 481 1957, Hanania & Irvine Nature 183 40 1959, Green & Saville J Chem Soc 3887 1956, Beilstein E-isomer 21 I 288, 21 III/IV 3504, 21/7 V 305.] |
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