| Identification | Back Directory | [Name]
Fostriecin | [CAS]
87810-56-8 | [Synonyms]
CL-1565A
Antibiotic CI-920
Antibiotic CL-1565A
Phosphotrienin, CI 920, CL 1565A, PD 110161, NSC 339638
(6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-phosphonooxy-1,7,9,11-tridecatetrenyl]-2H-pyran-2-one | [Molecular Formula]
C19H27O9P | [MDL Number]
MFCD00866380 | [MOL File]
87810-56-8.mol | [Molecular Weight]
430.39 |
| Hazard Information | Back Directory | [Uses]
Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The antitumour potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A. |
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